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  • Products → Microbiome → OMNIgene•SALIVA | OMR-610

    Total Nucleic Acid Collection Kit for Genomics and Microbiome (for Research Use only)

    Human and microbial DNA and RNA from a single saliva sample

    OMNIgene™•SALIVA DNA and RNA | OMR-610

    OMR-610 kit

    Set your multi-omic project up for success starting with the purpose-designed DNA and RNA sample collection device -- ideal for both host and microbial applications

    The OMNIgene•SALIVA DNA and RNA device is validated for the self-collection of saliva and the stabilization of total nucleic acids. Single-sample analysis with a true multi-omic collection device sets a NEW benchmark for at-home collection of total nucleic acids from saliva.

    Avoid the challenges of collecting and transporting multiple samples when you need to expand your research to include another analyte (DNA/RNA) or sample source (human/microbial). The OMNIgene•SALIVA DNA and RNA device brings together host genomics with the microbiome to support a multi-omic workflow by enabling scientists to extract both analytes (DNA and RNA) from a single sample.

    Combining datasets from host genomics, metagenomics, transcriptomics, and metatranscriptomics can accelerate scientific insights and research discoveries. Don't wait any longer to start your multi-omic project. Order the OMNIgene•SALIVA DNA and RNA device today!

    Future-proof your genomic and microbiome research today with a total nucleic acid collection and stabilization device

    Features and Benefits:

    • Validated for the self-collection of saliva and the stabilization of total nucleic acids during ambient temperature storage and shipping
    • Compatible with downstream applications including PCR/RT-PCR
    • All-in-one, patented, user-friendly design proven to reduce human error and improve donor compliance1
    • Single-sample analysis with a true multi-omic collection device

    The NEW benchmark for at-home collection of total nucleic acids from saliva

    DNA yield (μg) RNA yield (μg)
    N 15 15
    Mean ± SD 0.90 ± 0.89 0.72 ± 0.40
    Min, Max 0.08, 2.94 0.41, 1.85

    Table 1: Total DNA and RNA yields from a 250μL aliquot of OMNIgene•Saliva DNA and RNA extracted with QIAGEN® RNeasy® PowerMicrobiome Kit.

    OMNIgene Chart

    Figure 1: Quantification cycle (Cq) analysis for representative target genes across saliva samples collected in OMNIgene•SALIVA DNA and RNA (OMR-610)2

    Detection of target analytes after 21 days at room temperature or after 3 freeze-thaw cycles
    Human DNA Human DNA Positive
    Human RNA Human RNA Positive
    Bacterial DNA Bacterial DNA Positive
    Bacterial RNA Bacterial RNA Positive
    Viral DNA Viral DNA Positive
    Viral RNA Viral RNA Positive

    Analyte collection comparison

    OMNIgene•SALIVA
    DNA And RNA
    OMNIgene•Oral Oragene
    Human DNA OMNIgene Saliva Human DNA Positive OMNIgene Oral Human DNA Negative Oragene Human DNA Positive
    Human RNA OMNIgene Saliva Human RNA Positive OMNIgene Oral Human RNA Negative Oragene Human RNA Negative
    Microbial DNA OMNIgene Saliva Microbial DNA Positive OMNIgene Oral Microbial DNA Positive Oragene Microbial DNA Negative
    Microbial RNA OMNIgene Saliva Microbial RNA Positive OMNIgene Oral Microbial RNA Positive Oragene Microbial RNA Negative

    Specifications and attributes

    Saliva sample to stabilization solution ratio 1 mL/1 mL
    Number of extractions per kit (250μL per extraction) Up to 8
    Yields suitable for downstream applications i.e., qPCR, RT-qPCR, genotyping
    Freeze-thaw and temperature fluctuation stability -20°C to +50°C
    Room temperature stability for the detection of human and microbial DNA and RNA 21 days
    Barcoded for full sample traceability (128C format) OMNIgene Oral Microbial RNA Positive
    OMNIgene Device
    See the product up close
    OMR 610 kit package photo

    Increase ease of use and maximize collection compliance

    Study participants (N = 507) successfully completed entire user workflow of kit registration, sample collection, and shipping sample to processing laboratory

    • ≥ 96.5% of study participants agreed that collection instructions were easy to find1
    • ≥ 96.1% of study participants agreed that collection instructions were easy to understand1
    Icon link to the complete donor instruction

    View donor user instructions

    SALIVA FOR GENOMICS

    The trusted legacy of Oragene and ORAcollect – all-in-one, easy-to-use sample collection kits for individuals of all ages.

    View Genomics Collection Devices

    Beyond ORAL microbiome

    The OMNIgene® line of products also includes all-in-one systems for quantitative profile analysis pf the gut and vaginal microbiome.

    View All Microbiome Collection Devices

    Literature

    Data Sheets

    PD-BR-00387: OMNIgene•SALIVA DNA and RNA data sheet [PDF]

    Collection Instructions

    OMNIgene•SALIVA DNA and RNA | OMR-610 collection instructions

    Protocols

    The OMNIgene™•SALIVA DNA and RNA (OMR-610) purification protocol for total nucleic acids, including viral nucleic acids, using Applied Biosystems MagMAX™ Viral/Pathogen Nucleic Acid Isolation Kit

    The purification of human genomic DNA from OMNIgene™•SALIVA DNA and RNA (OMR-610) using prepIT™•L2P reagent

    The purification of human RNA from OMNIgene™•SALIVA DNA and RNA (OMR-610) samples using the QIAGEN RNeasy® Micro Kit and QIAGEN RNeasy® Mini Kit

    The OMNIgene™•SALIVA DNA and RNA (OMR-610) purification protocol for viral total nucleic acids using Applied Biosystems MagMAX™ Viral/Pathogen Nucleic Acid Isolation Kit

    OMNIgene™•SALIVA DNA and RNA (OMR-610) purification protocol for human, bacterial and viral total nucleic acids using QIAGEN AllPrep PowerViral DNA/RNA Kit

    Recommendations

    PD-PR-01036: Storage recommendations for samples collected with OMNIgene® products [PDF]

    Safety Data Sheets

    PD-MSDS-00150: OMNIgene•SALIVA DNA and RNA MSDS UK [PDF]

    Videos

    OMNIgene™ SALIVA DNA and RNA device user instructions for collection and stabilization of human and microbial DNA and RNA from saliva.

    Accessories

    Mailing Accessories

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    Customization Options

    For Research Use Only. Not for use in diagnostic procedures

    1 Based upon results from the Oragene™ •Dx human factors studies [K141410 and K192920]

    2 To evaluate viral nucleic acids, samples were spiked with both a DNA virus and an RNA virus.

    Nucleic acid extractions were performed at baseline (T0) and after > 21 days of storage (T21) followed by qPCR or RT-qPCR analysis using primers and/or probes specific for the representative gene targets. Data are presented as a scatter plot, where each point represents an extracted sample from one individual, with box plot overlay showing median and quartiles.

    Full terms and conditions for all DNA Genotek products are available here.

    DNA Genotek's sample collection devices and nucleic acid stabilization chemistries are protected by issued and pending patents in numerous countries around the world.

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    DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc. (NASDAQ: OSUR), focuses on providing high-quality biological sample collection products and end-to-end services for human genomics, microbiome and infectious disease applications. The Company's Oragene•Dx and ORAcollect•Dx product lines are the first and only FDA 510(k) cleared saliva-based DNA collection devices for in vitro diagnostic use. DNA Genotek also offers Research Use Only products to collect and preserve large amounts of DNA or RNA from multiple sample types. DNA Genotek markets its products worldwide and has a global customer base with thousands of customers in over 100 countries.

    © 2025 DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc., all rights reserved.

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      • All research DNA & RNA collection kits (saliva)
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        • NEW OMNIgene•SALIVA | OMR-610
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        • prepIT•L2P | PT-L2P (saliva)
        • prepIT•Q2A | PT-Q2A (saliva)
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          • NEW OMNIgene•SALIVA | OMR-610
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          • PRAS Dilution blanks
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