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"I found the Oragene/saliva sample collection kit very simple to use. The protocol was easy to follow and time-saving permitting me to perform the extraction amplification and analysis steps in a single day."

Melissa Boweman,
Plexagen Diagnostics Ltd.

DNA Genotek has made the human readable barcode larger and easier to read
on the ORAcollect.Dx (OCD-100) product. Please see the Product Change Notification here.

  • Overview
  • Literature

ORAcollect•Dx (OCD-100)


Collect high quality DNA samples for molecular diagnostics

ORAcollect®•Dx is a robust, painless and easy-to-use DNA collection kit. ORAcollect•Dx is designed to collect, stabilize and protect DNA samples. Unlike buccal swabs, ORAcollect•Dx samples yield larger amounts of high quality human DNA and integrates easily into existing laboratory workflows.

DNA collection with ORAcollect•Dx provides:

  • A fast, easy and reliable DNA sample with no drying time required
  • Stabilized DNA at ambient temperature
  • High quality DNA for use in downstream molecular applications
  • Flexible processing with seamless integration into existing workflows

ORAcollect•Dx is an FDA cleared device†. Molecular diagnostic and laboratory developed test manufacturers can reduce the time and regulatory burden of their own FDA submissions by leveraging the 510(k) clearance of ORAcollect•Dx.


ORAcollect•Dx is a superior alternative to buccal swabs and offers several advantages:

  • Collection of sample is simple and gentle for donor
  • Efficient collection is ideal for clinical workflows
  • DNA integrity is maintained at ambient temperature for transportation via regular post
  • Bacteriostatic reagent inhibits growth of bacteria from time of sample collection to processing
  • Liquid sample (no cutting of tips) eliminates manual steps, reduces the chance of errors and cross contamination, while facilitating efficiency in the lab
  • High quality DNA sample enables downstream analysis with proven clinical utility
  • Format optimizes laboratory efficiency
    • Use with liquid handling robots
    • Minimal hands on technician time
    • Compatible with standard labware
    • Integrated barcode on tube for workflow efficiency and sample traceability

Collection method comparison

Buccal swabs
ORAcollect•DX (OCD-100)
No drying time required
Specimen stability at ambient temperature
Liquid sample
Standardized format for high-throughput processing
Eliminates cross contamination
Integrated barcode for sample traceability
FDA cleared
Microbial contamination
T0 = 14%, T30 days = 24%‡
T0 = 4%, T60 days = 4%**
Median DNA yield
0.7 µg‡
2.6 µg*
Molecular weight
< 23 kb
> 23 kb

† Panford-Walsh R., Doukhanine E. and Bouevitch A. (2011). Comparison of DNA from samples collected using ORAcollect•DNA (OCR-100) vs. buccal swabs. DNA Genotek. PD‑WP-00021.
* Data was obtained by testing 156 samples from 156 donors and DNA was extracted using the QIAamp® DNA Mini kit (QIAGEN®).
** Data was obtained by testing 30 samples from 30 donors.

Full terms and conditions for all DNA Genotek products are available here.

ORAcollect®•Dx has been cleared for in vitro diagnostic use in the U.S.A. † FDA cleared for in vitro diagnostic use with the eSensor® Warfarin Sensitivity Saliva Test.

DNA Genotek's sample collection devices and nucleic acid stabilization chemistries are protected by issued and pending patents in numerous countries around the world.
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