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There's an estimated 3 billion DNA bases in our genome. A complete 3 billion base genome would take 3 gigabytes of storage space.
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Contact:

Marc Rubenfield
Manager Technical Operations
500 Cummings Center,
Suite 2450
Beverly, MA 01915
978-867-2673
MJRubenfield
@beckman.com

Beckman Coulter Genomics (formerly Cogenics)

Description of services:

  • Genome characterization and sequencing
  • Genotyping assay development and validation
  • Gene expression profiling and validation
  • Drug efficacy and safety-related analysis
  • Biologics evaluation and safety testing
  • Data management, analysis and interpretation
  • Sample management and biobanking
  • Scientific consulting

Contact:

Rama Modali President
9000 Virginia Manor Rd., Suite 207
Beltsville, MD
20705
301-470-3362
rmodali@bioserve.com

BioServe Biotechnologies, Ltd.

Description of services:

DNA and RNA extractions, Realtime PCR analysis, SNP analysis using Sequenoms iPLEX system, expression analysis using the Taqman system. Manual extraction of RNA and DNA. We utilize our proprietary DNA extraction reagents, DNAQuick for DNA extraction from most of the sources. We also utilize Qiagen column protocols for some sample types. For RNA extractions we typically use Tri-reagent method and some times utilize Qiagen column based protocols. We have Standard Operating Protocols (SOPs) for all the different applications.

Lab Location and Locations served:

BioServe Biotechnologies, Ltd.
9000 Virginia Manor Rd., Suite 207
Beltsville, MD 20705

 

Clinical Diagnostic Laboratory, Institute of Genomic Medicine

(CLIA Certified)

Description of services:

Molecular Diagnostics

  • DNA mutation testing for twenty single gene disorders, Ashkenazi Jewish panel, thrombophilia, mitochondrial DNA disorders.
  • Microarray-based comparative genomic hybridization for mental retardation/developmental delay (Agilent Array)
  • DNA sequence analysis for disease predisposition genes.

Cytogenetics

  • Chromosome and FISH analysis on amniotic fluid, peripheral blood, products of conception, fibroblasts, bone marrow, lymph node and solid tumors.

Biochemical Genetics

  • Amino acid and organ acid disorders, mucopolysaccharidoses, defects of carnitine metabolism Diagnostic Microarray Services.
  • Affymetrix Gene Expression, SNP analysis and Targeted Genotyping available in our clinical lab at the Center for Applied Genomics www.cag.icph.org
  • Proteomic Diagnostics Clinical proteomic assays using MSIA technology which couples antibody affinity capture to mass spectrometry.

Proteomic Diagnostics

Clinical proteomic assays using MSIA technology which couples antibody affinity capture to mass spectrometry.

Lab location and locations served:

Institute of Genomic Medicine
MSB F-656, New Jersey Medical School
185 South Orange Ave.
Newark, NJ 07103

Contact:

Heather Newkirk, Ph.D.
Executive Director of Molecular Diagnostics
8433 Quivira Rd.
Lenexa, KS
66215
t: 913-693-8899
email: newkirkh@crlcorp.com


Clinical Reference Laboratory

CLIA certified services for custom molecular assays. CRL also performs clinical trials, insurance, toxicology and bioanalytical testing.

Contact:

Kellie Yarnell
kyarnell@
expressionanalysis.com

Sales & Business
Development
Tel: 724-935-7029 or
866-293-6094

Expression Analysis, Inc.

Expression Analysis provides expression profiling and genotyping services using Affymetrix, Illumina, Luminex and Applied Biosystems' TaqMan® technologies. As the leading provider of microarray services in clinical trials, Expression Analysis offers solutions for challenging specimens, such as blood and FFPE tissues, as well as nucleic acid isolation and data analysis services. The company also performs diagnostic assays in its CLIA and GLP-compliant laboratory.

Lab location and locations served:

The Expression Analysis facility is located in Durham, NC. Our services are provided worldwide to a variety of clients including most of the top 10 pharmaceutical companies.

Expression Analysis, Inc.
4324 South Alston Avenue, Suite 101
Durham, NC 27713

Contact:

Leslie Steele
leslie.steele@sickkids.ca
Nicole Parkinson
nicole.parkinson@
sickkids.ca

Tel: (416) 813-6590
Fax: (416) 813-7732

The Molecular Genetics Laboratory
The Hospital for Sick Children

Clinical molecular diagnostic laboratory (see website for details of services offered)

Lab location:

Molecular Genetics Laboratory
555 University Ave., Roy C. Hill Wing, Rm. 3421
Toronto, ON, Canada
M5G 1X

 

Contact:

Jean Reiss
Lab manager
710 Westwood Plaza, Room 3235 Los Angeles, CA 90095 jreiss@mednet.ucla.edu
Tel: 310-267-2931

UCLA Biomarker Innovations Laboratory
The Hospital for Sick Children

Description of services:

The UCLA Biomarker Innovations Laboratory (BIL) is a California state licensed and CLIA-certified clinical laboratory founded by Drs. Scott Binder and David Seligson, pathologist-scientists, and is located at one of the world\'s leading hospitals and academic institutions - the David Geffen School of Medicine at the University of California, Los Angeles (UCLA).

Applications:

The BIL is currently offering the J&J/Veridex CTC (Circulating Tumor Cell Detection in whole blood) assay for monitoring metastatic breast, colon and prostate cancers. EGFRvIII RT PCR Gene Expression -Glioblastoma multiforme (GBM) is the most aggressive brain tumor in adults and remains incurable despite multimodal intensive treatment regimens. EGFRvIII is a truncated extracellular mutant of the EGF receptor (EGFR) commonly found in GBMs that confers enhanced tumorigenic behavior. This assay was developed by the UCLA Neurological research team and the laboratory procedures has been validated by the BIL. The assay includes RNA extraction from 4-8 10 um thickness of tissue sections, reverse transcribe the RNA to cDNA synthesis and followed by SYBR Green Real Time PCR using Roche LightCycler 480.

Lab Location and Locations served:

UCLA Biomarker Innovations Laboratory
710 Westwood Plaza, Room 3235
Los Angeles, CA 90095

Contact:

Hugo Alberto Barrera Saldaña
General

Camino de las
Alondras #240
Monterrey, Nuevo León, México, 64630
habarrera@gmail.com
Tel: 52 (81) 81 43 89 43

Vitagenesis, S.A. de C.V.

Description of services:

Genomic Analysis (Paternity Test, Papillomavirus Genotypification, detection of KRAS, JAK-2 and Factor V mutation).

Lab location and locations served:

Vitagenesis, S.A. de C.V.
Boulevard Puerta del Sol #1005
Monterrey, Nuevo León, México, 64630

"DNA Genotek's Partner Program is enabling partners like us to successfully grow our businesses by delivering the tools and support to help us take advantage of the growing genomics market.

DNA Genotek is committed to providing a robust partner program to further improve our ability to help our clients with their processing, long term storage and distribution of human genetic samples using the Oragene family of products."

Steve Turner,
Facility Manager,
Genetic Repositories Australia

© 2012 DNA Genotek Inc., a subsidiary of OraSure Technologies, Inc., all rights reserved.